针灸治疗糖尿病神经性疼痛的疗效：系统综述和荟萃分析

WTW

Effects of acupuncture therapy in diabetic neuropathic pain: A systematic review and meta-analysis
Abstract

Objective: To evaluate the effectiveness of acupuncture in relieving diabetic neuropathic pain and to establish a more reliable and efficient foundation for acupuncture practice in diabetes care.

Methods: The Chinese National Knowledge Infrastructure, Wanfang database, Chongqing Weipu, Chinese Biomedical Literature Database, PubMed, Embase, and Cochrane Library were all searched for a randomized controlled trial research of acupuncture for DNP. Two researchers independently performed literature screening, quality evaluation, and data extraction. After selecting studies and extracting data, we conducted the data analysis using RevMan 5.4 and Stata 14.0. The quality was assessed using the Cochrane Risk of Bias Assessment Tool.

Results: An extensive review of 19 studies involving 1276 patients up to April 29, 2023, found that acupuncture was successful in improving pain intensity [MD= -1.09; 95% CI (-1.28, -0.89), P < 0.00001], clinical efficacy indicating pain changes [RR= 1.22; 95% CI (1.15, 1.29), P < 0.00001], and clinical neuropathy [MD= -1.55; 95% CI ( -3.00, -0.09), P = 0.04] in DNP patients. Quality of life was also improved, with few side effects reported.

Conclusion: According to this meta-analysis, acupuncture therapy significantly improved the clinical efficacy of pain intensity, pain changes, and clinical neuropathy in patients with DNP, improved the quality of life of patients to a certain extent, and had lower side effects. This discovery provides evidence-based and practical recommendations for the treatment of DNP patients.

Keywords: Acupuncture therapy; Diabetes; Diabetic neuropathic pain; Meta-analysis; Systematic review.

摘要目的：评价针灸治疗糖尿病神经性疼痛的疗效，为针灸治疗糖尿病奠定更可靠、有效的基础。方法：检索中国国家知识基础设施、万方数据库、重庆卫普、中国生物医学文献数据库、PubMed、Embase和Cochrane图书馆，进行针刺治疗DNP的随机对照试验研究。两名研究人员独立进行了文献筛选、质量评估和数据提取。在选择研究并提取数据后，我们使用RevMan 5.4和Stata 14.0进行了数据分析。使用Cochrane偏倚风险评估工具对质量进行评估。结果：截至2023年4月29日，对涉及1276名患者的19项研究进行了广泛回顾，发现针灸在DNP患者中成功地改善了疼痛强度[MD=-1.09；95%CI（-1.28，-0.89），P<0.00001]、指示疼痛变化的临床疗效[RR=1.22；95%CI[1.15，1.29），P<0.00001]和临床神经病变[MD=-1.55；95%CI【-3.00，-0.09），P=0.04]。生活质量也得到了改善，几乎没有副作用报告。结论：根据该荟萃分析，针灸治疗显著改善了DNP患者的疼痛强度、疼痛变化和临床神经病变的临床疗效，在一定程度上提高了患者的生活质量，副作用较低。这一发现为DNP患者的治疗提供了循证和实用的建议。关键词：针灸疗法；糖尿病糖尿病神经性疼痛；荟萃分析；系统审查。

https://linkinghub.elsevier.com/retrieve/pii/S0965-2299(23)00079-1