The durable effect of acupuncture for episodic migraine: a systematic review ...

WTW

The durable effect of acupuncture for episodic migraine: a systematic review and meta-analysisHangyu Shi 1 2, Runyu Miao 2 3, Shuai Gao 1, Lili Zhu 1, Jiufei Fang 1, Zhishun Liu 1


Affiliations expand

• PMID: 37746146
  
• PMCID: PMC10514352
  
• DOI: 10.3389/fnins.2023.1211438
  

Free PMC article
Abstract

Background: Migraine is a common and recurrent type of headache. Avoiding trigger factors is not often successful in reducing headache frequency, duration, and severity. Prophylactic medications may be effective but are limited by strict indications and daily medication intake. This review aimed to investigate the durable effect of acupuncture on episodic migraine.

Methods: Seven databases including Medline, Embase, PubMed, etc., were searched for English and Chinese literature from their inception to 23 November 2022. Two independent reviewers screened the retrieved studies and extracted the data. Primary outcomes were monthly migraine days, monthly migraine attacks, and VAS score at 3 months post-treatment. The risk of bias in included studies was assessed using the Cochrane Risk of Bias 2.0 tool. Meta-analysis was conducted where applicable.

Results: Fifteen studies were included in this review. Acupuncture reduced the number of migraine attacks (MD -0.68; 95% CI -0.93, -0.43; p < 0.001), the number of days with migraine (MD -0.86; 95% CI -1.18, -0.55; p < 0.001), and VAS score (MD -1.01; 95% CI -1.30, -0.72; p < 0.001) to a greater degree than sham acupuncture at 3 months after treatment. Significant differences in reducing pain intensity of migraine in favor of acupuncture compared with waitlist (MD -1.84; 95% CI -2.31, -1.37; p < 0.001) or flunarizine (MD -2.00; 95% CI -2.35, -1.65; p < 0.001) at 3 months after treatment were found, and the differences reached the minimal clinically important difference (MCID).

Conclusion: This review found that the durable effect of acupuncture for episodic migraine lasted at least 3 months after treatment. More high-quality studies with longer follow-up periods in the future are needed to confirm the findings.

Keywords: RCTs; acupuncture; durable effect; migraine; systematic review.

针刺治疗发作性偏头痛的持久疗效：系统综述和荟萃分析石航宇1 2，苗润玉2 3，高帅1，朱丽丽1，方久飞1，刘志顺1附属关系扩展PMID:37746146 PMCIDMC10514352 DOI:10.3389/fnins.2023.1211438免费PMC文章摘要背景：偏头痛是一种常见且反复发作的头痛。避免触发因素往往不能成功地降低头痛的频率、持续时间和严重程度。预防性药物可能是有效的，但受到严格的适应症和每日药物摄入的限制。本文旨在探讨针刺治疗发作性偏头痛的持久疗效。方法：检索Medline、Embase、PubMed等7个数据库自成立至2022年11月23日的中英文文献。两名独立评审员对检索到的研究进行筛选并提取数据。主要结果为每月偏头痛天数、每月偏头痛发作次数和治疗后3个月VAS评分。纳入研究中的偏倚风险使用Cochrane偏倚风险2.0工具进行评估。在适用的情况下进行荟萃分析。结果：本综述包括15项研究。在治疗后3个月，针灸比假针灸在更大程度上减少了偏头痛发作次数（MD-0.68；95%CI-0.93，-0.43；p<0.001）、偏头痛天数（MD-0.86；95%CI-1.18，-0.55；p<0.001）和VAS评分（MD-1.01；95%CI-1.00，-0.72；p<0.001）。在治疗后3个月，与等待名单（MD-1.84；95%CI-2.31，-1.37；p＜0.001）或氟桂利嗪（MD-2.00；95%CI-2.35，-1.65；p＜001）相比，针灸在减轻偏头痛疼痛强度方面存在显著差异，并且差异达到最小临床重要差异（MCID）。结论：本综述发现针刺治疗发作性偏头痛的持久效果在治疗后至少持续3个月。未来需要更多高质量的研究和更长的随访期来证实这一发现。关键词：随机对照试验；针灸持久效果；偏头痛系统审查。