而且,如果早发性结直肠癌发病率上升是由于检查率增加,那么应该有更多患者在早期诊断,也就是说筛查出来的患者更可能为局部疾病。然而,与前面研究中年轻患者更多为晚期疾病一样,该研究也发现,40~44岁人群的局部疾病增多,但45~49岁人群未增多;而且,所有年龄组的远处转移疾病增长都高于局部疾病(年增长:2.9% vs 1.1%)。
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[9]《居民常见恶性肿瘤筛查和预防推荐》